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Pharmacogenomics reports

February 2024
What are Pharmacogenomics Reports?

Pharmacogenomics reports categorise medications by revealing how an individual's genetic composition affects their reactions to specific medications. This personalised approach to medication classification, helps providers make informed decisions about medication selection and dosing, optimising therapeutic outcomes while minimising adverse effects. Medication classification in Pharmacogenomics Reports involves categorising drugs based on an individual’s genetic composition. Patients are classified as Ultrarapid, Poor, Intermediate and Normal Metabolisers based on genetic variants affecting drug metabolism. This classification informs dosing adjustments.

Who can access it?

Currently the report is available to L1 users (Primary Providers) following ‘break the privacy seal’ and obtaining consent from the patient.

How can I use this information?

The Pharmacogenomics report provides clinicians with valuable information regarding the genetic profile of the patient and its influence and response to specific medications. This supports physicians in prescribing medication tailored to each patient, to enhance treatment outcomes and minimise the occurrence of adverse drug events.

What does the report contain?

The report contains four detailed segments
• Actionable Findings – lists medications which fall under the following categorisation - ultrarapid, poor metaboliser or intermediate based on the patient’s genetic composition.
Note: Normal metabolisers will not be listed here.
• Detailed Guideline – Provides a detailed list of all medications that were tested based on the patient’s genetic composition as well as recommendations and implications if administered
• Complete Summary – Lists a concise view of all medications that were tested based on the patient’s genetic composition
• Citations – Lists the resource citations

Why can’t I see the pharamacogenomics report for my patient?

The following reasons may include:
1.  The pharmacogenomics report is not yet generated.
2. You have not selected to ‘Break the Privacy seal’

How do I know if my patient has a Pharmacogenomics Report?

Pharmacogenomics reports are linked to the EGP participant tag. If a patient has an available Pharmacogenomics Report, the notification tag in the patient banner will display: "EGP Participant (PGX report available)". Alternatively, you can ‘Break the privacy seal’ and check the report through the clinical documents.

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